Clinical Trials repository link available on JCO.org. Authors’ disclosures of potential conflicts of interest and author contributions are found at the end of this article. The trial was conducted under the auspices of Institut National du Cancer. Supported in part by Roche and Sanofi- Aventis together with a grant of the French National Program of Research Programmes hospitaliers de recherche clinique. Submitted Septemaccepted Decempublished online ahead of print at on March 1, 2010. VOLUME 28 NUMBER 10 APJOURNAL OF CLINICAL ONCOLOGY O R I G I N A L R E P O R T Comparison of Two Neoadjuvant Chemoradiotherapy Regimens for Locally Advanced Rectal Cancer: Results of the Phase III Trial ACCORD 12/0405-Prodige 2 Jean-Pierre Gérard, David Azria, Sophie Gourgou-Bourgade, Isabelle Martel-Laffay, Christophe Hennequin, Pierre-Luc Etienne, Véronique Vendrely, Eric François, Guy de La Roche, Olivier Bouché, Xavier Mirabel, Bernard Denis, Laurent Mineur, Jean-François Berdah, Marc André Mahé, Yves Bécouarn, Olivier Dupuis, Gérard Lledo, Christine Montoto-Grillot, and Thierry Conroy See accompanying editorial on page 1623 From the Centre Antoine-Lacassagne Université Nice Sofia Antipolis, Nice Centre Val d’Aurelle, Montpellier Centre Léon Bérard Hôpital privé Jean Mermoz, Lyon Hôpital St Louis Fédération Nationale des Centres de Lutte Contre le Cancer, Paris Clinique Armoricaine de Radiologie, St Brieuc Hôpital Saint André, Bordeaux Institut de Cancérologie de La Loire, St Priest en Jarez Centre Hospitalier Universitaire Robert Debré, Reims Centre Oscar Lambret, Lille Hôpital Pasteur, Colmar Institut Ste Catherine, Avignon Clinique Ste Marguerite, Hyères Centre René Gauducheau, Nantes St Herblain Institut Bergonié, Bordeaux Clinique Victor Hugo, Le Mans and Centre Alexis Vautrin, Vandoeuvre-Les-Nancy, France.
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